2 sets of RAM: 1333 and 1600

[jackbandit73]

I wanted some help regarding RAM I purchased awhile back. Here are my system specs:

Mobo: Asus M489GTD Pro
CPU: AMD Phenom ii x6 1055t

I have 2 sets of RAM:
F3-10666CL9-4GBRL 2 sticks at 8GB
and
F3-12800CL9-2GBRL 2 sticks at 4GB XMP
12 GB of RAM in total.

Currently I am running all RAM at 10666 (DDR3 1333).

I am wondering if running them at 1333 is inhibiting the entire system since I have a mix of 2-1333 and 2-1600 XMP sticks.

To my understanding, XMP need to be run alone for optimum performance.

Would the system run a lot smother if I purchased another set of the f3-10666CL9-4GBRL and simply took out the 2-2gb 1600 XMP set?

Thanks for the help

[Tradesman]

If running at 1333, with all four sticks that means the 1600 sticks are also running at 1333 and probably 9-9-9-twenty something, while they will run with these timings it's not optimal for the 1600 sticks, ideally at 1333 they'd run at 8-8-8-24 or better...It shouldn't have a negative affect on the system...but it's possible, it won't hurt anything physically or damage anything, but if getting any BSODs might want to raise the DRAM voltage a pinch to smooth things out...maybe add + .03 to the DRAM voltage

[jackbandit73]

Thanks.

I'll turn up the voltage +.03 and see if it makes a difference. I don't get BSOD but I do get occasional lock up and freezes where I can move my mouse but nothing else seems to work. It may be something else other than my RAM though. I'll report back.

[Tradesman]

Can try each set by themselves and if no problems then it's prob the combo, can try adjusting the DRAM voltage and/or the MC voltage